Craig Mayer, Nick WIlliams, Vojtech Huser
Lister Hill National Center for Biomedical Communications, National Library of Medicine, NIH, Bethesda, MD

See the full regCTG repository at https://github.com/lhncbc/CRI/tree/master/regCTG

To return to the list of conditions and view other reports go to https://lhncbc.github.io/CRI/regCTG/regCTG-condition_report_links.html


Study Counts

Type Study_count
Total_Studies 194
interventional 134
Observational 57
Registry 3

Studies over Time by Start Date

```

Interventional Trials

Intervention Type

intervention_type Study_Count
Behavioral 42
Other 28
Device 21
Drug|placebo 10
Procedure 6
Device|Other 5
Drug 4
Diagnostic Test 3
Dietary Supplement|placebo 3
Behavioral|Other 2
Drug|Other 2
Other|placebo 2
Behavioral|Device|placebo 1
Biological|placebo 1
Device|Other|Procedure 1
Device|placebo 1
Device|Procedure 1
Dietary Supplement|Other 1

Count of Studies by Intervention (normalized and mapped)

Interventions over Time

Yearly studies for each intervention by start date

Studies by Country

Country Study_Count
United States 91
Canada 20
Norway 4
Denmark 3
France 3
NA 3
Afghanistan 2
Finland 2
Canada|France|Israel 1
China 1
France|Monaco 1
Iraq 1
Malaysia 1
United States|Canada|New Zealand 1

Sites per Study

Site_count Study_Count
1 105
2 13
3 7
4 2
5 2
6 1
7 1
8 1
11 1
18 1

Phase

Phase Study_Count
N/A 112
Phase 2 10
Phase 1 6
Phase 1/Phase 2 3
Early Phase 1 1
Phase 3 1
Phase 4 1

Number of Arms

Number_of_Arms Count_of_Studies
1 16
2 92
3 11
4 10
5 2
NA 3

Enrollment Metrics by Phase

Measure Early.Phase.1 N.A Phase.1 Phase.1.Phase.2 Phase.2 Phase.3 Phase.4
Min. 20 3.0000 16.00000 20.0000 20.00 NA 143
1st Qu. 20 45.7500 22.50000 110.0000 44.00 NA 143
Median 20 83.0000 32.00000 200.0000 55.00 NA 143
Mean 20 284.1786 35.83333 149.3333 70.90 NaN 143
3rd Qu. 20 200.0000 38.50000 214.0000 94.75 NA 143
Max. 20 4000.0000 75.00000 228.0000 180.00 NA 143

Trial Group Type

group_type Group_Count
Experimental 143
Active Comparator 58
No Intervention 40
Placebo Comparator 25
Sham Comparator 11
Other 6
NA 3

Intervention Model

intervention_model Study_Count
Parallel Assignment 101
Single Group Assignment 19
Crossover Assignment 7
Factorial Assignment 5
Sequential Assignment 1
NA 1

Primary Purpose

primary_purpose Study_Count
Treatment 88
Diagnostic 13
Prevention 11
Screening 8
Other 7
Basic Science 2
Health Services Research 2
Supportive Care 2
NA 1

Observational Studies

Studies by Country

Country Study_Count
United States 41
Denmark 5
Ireland 2
Israel 2
Canada 1
China 1
France 1
France|Monaco 1
France|Spain 1
NA 1
Sweden 1

Sites per Study

Site_count Study_Count
1 39
2 6
3 1
4 2
5 2
6 3
8 1
11 1
15 2

Enrollment Metrics

Measure Observational
Min 3.000
1st Qu 63.000
Median 175.000
Mean 1813.263
3rd Qu 477.000
Max 45777.000

Observation Model

observational_model Study_Count
Cohort 37
Case-Control 12
Case Control 4
Case-Only 3
Ecologic or Community 1

Time Perspective

time_perspective Study_Count
Prospective 43
Cross-Sectional 8
Retrospective 6

Registries

Studies by Country

Country Study_Count
NA 2
United States 1

Sites per Study

Site_count Study_Count
1 3

Enrollment Metrics

Measure Registries
Min 42.0000
1st Qu 201.0000
Median 360.0000
Mean 300.6667
3rd Qu 430.0000
Max 500.0000

Registry Model

observational_model Study_Count
Case-Control 1
Case-Only 1
Cohort 1

Time Perspective

time_perspective Study_Count
Prospective 2
Cross-Sectional 1

Follow-up

target_duration Study_Count
1 Year 2
6 Months 1

Overview of Studies

Interventional Trials

#If less then 500 trials

nct_id brief_title link overall_status source primary_completion_date
NCT04288167 Biochemical Diagnostics of Mild Traumatic Brain Injury (TBI) and Concussion in Children and Adolescents https://ClinicalTrials.gov/show/NCT04288167 Recruiting Medicortex Finland Oy 2021-02-28
NCT04044456 Combining Attention and Metacognitive Training to Improve Goal Directed Behavior in Veterans With TBI https://ClinicalTrials.gov/show/NCT04044456 Recruiting VA Office of Research and Development 2021-12-01
NCT03478059 Dual-task Assessment and Rehabilitation for Individuals With Residual Symptoms After mTBI https://ClinicalTrials.gov/show/NCT03478059 Completed Allina Health System 2019-06-30
NCT03819608 Neuromodulation and Neurorehabilitation for mTBI Plus PTSD https://ClinicalTrials.gov/show/NCT03819608 Recruiting Edward Hines Jr. VA Hospital 2022-03-31
NCT03306563 Rapid Biochemical Diagnostics of Traumatic Brain Injury https://ClinicalTrials.gov/show/NCT03306563 Completed Medicortex Finland Oy 2019-02-28
NCT03237676 The Effect of Cognitive Rehabilitation Therapy in Improving Cognitive Function of Attention Following Mild Traumatic Brain Injury https://ClinicalTrials.gov/show/NCT03237676 Recruiting University of Malaya 2019-10-30
NCT03230656 Cognitive-Communication Screening and Early Therapy for Adults With Mild TBI https://ClinicalTrials.gov/show/NCT03230656 Recruiting Northern Arizona University 2020-12-31
NCT03221218 Enhanced Screening for Early Treatment Targets After MTBI https://ClinicalTrials.gov/show/NCT03221218 Active, not recruiting University of British Columbia 2019-10-30
NCT03217695 A Study on the Effect of Mindfulness-based Yoga on Youth With Persistent Concussion Symptoms https://ClinicalTrials.gov/show/NCT03217695 Completed Holland Bloorview Kids Rehabilitation Hospital 2016-10-07
NCT03215082 Seeing-Moving-Playing: Early Rehabilitation Utilizing Visual and Vestibular Technology Following Traumatic Brain Injury https://ClinicalTrials.gov/show/NCT03215082 Recruiting McGill University Health Centre/Research Institute of the McGill University Health Centre 2020-10-31
NCT03195738 Feasibility of a Cognitive Intervention for Youth Post Concussion https://ClinicalTrials.gov/show/NCT03195738 Completed Holland Bloorview Kids Rehabilitation Hospital 2016-03-30
NCT03180905 ImPACT Normative Extension https://ClinicalTrials.gov/show/NCT03180905 Recruiting ImPACT Applications, Inc. 2020-06-30
NCT03170856 The Effects of a Sub-maximal Exercise Program on Adolescents Who Sustained a Concussion https://ClinicalTrials.gov/show/NCT03170856 Recruiting Boston Children’s Hospital 2019-11-30
NCT03123822 To Compare the Effectiveness of 3 Different Types of Lens and Lens Coating in Eliminating Symptoms for Children With Prolonged Visual Symptoms Due to a Concussion. https://ClinicalTrials.gov/show/NCT03123822 Recruiting University of Alabama at Birmingham 2022-01-31
NCT03084211 Prescribed Light Exercise for ED Patients With MTBI https://ClinicalTrials.gov/show/NCT03084211 Completed Mount Sinai Hospital, Canada 2019-10-03
NCT03034720 Collaborative Care Model for the Treatment of Persistent Symptoms After Concussion Among Youth https://ClinicalTrials.gov/show/NCT03034720 Completed Seattle Children’s Hospital 2020-05-29
NCT03014492 Concussion Prevention in Soccer https://ClinicalTrials.gov/show/NCT03014492 Completed Children’s Hospital Medical Center, Cincinnati 2017-12-31
NCT02988596 Role of Rehabilitation in Concussion Management: A Randomized Controlled Trial https://ClinicalTrials.gov/show/NCT02988596 Completed University of North Carolina, Chapel Hill 2019-08-31
NCT02969824 Post-acute Structured Exercise Following Sport Concussion https://ClinicalTrials.gov/show/NCT02969824 Recruiting University of Toronto 2021-01-31
NCT02959294 Use of Adipose-Derived Stem/Stromal Cells in Concussion and Traumatic Brain Injuries https://ClinicalTrials.gov/show/NCT02959294 Recruiting Healeon Medical Inc 2023-11-30
NCT02959216 Aerobic Exercise for Concussion https://ClinicalTrials.gov/show/NCT02959216 Active, not recruiting Children’s Hospital of Philadelphia 2020-07-31
NCT02922569 Home-Based, Online, Mindfulness and Cognitive Training for Soldiers and Veterans With TBI https://ClinicalTrials.gov/show/NCT02922569 Active, not recruiting Posit Science Corporation 2020-08-30
NCT02872480 Acute Concussion Therapy Intervention Training in Healthy and Concussed Participants https://ClinicalTrials.gov/show/NCT02872480 Completed University of North Carolina, Chapel Hill 2017-02-28
NCT02868671 Acupuncture for Mild Traumatic Brain Injury With Post-traumatic Stress Disorder : A Functional Magnetic Resonance Imaging Study https://ClinicalTrials.gov/show/NCT02868671 Recruiting First Affiliated Hospital Xi’an Jiaotong University 2020-08-31
NCT02850926 Effect of Soccer Head Gear to Reduce Concussions https://ClinicalTrials.gov/show/NCT02850926 Completed University of Wisconsin, Madison 2018-06-30
NCT02844946 One-Day Life Skills Workshop for Veterans With TBI, Pain and Psychopathology https://ClinicalTrials.gov/show/NCT02844946 Completed VA Office of Research and Development 2018-09-03
NCT02819778 Study Assessing Evaluation of the Interest of Serum S100B Protein Determination in the Management of Pediatric Mild Traumatic Brain Injury https://ClinicalTrials.gov/show/NCT02819778 Recruiting University Hospital, Clermont-Ferrand 2020-04-30
NCT02812225 Non-blinded Data Collection Study of Concussion Using the BrainPulse(TM) https://ClinicalTrials.gov/show/NCT02812225 Recruiting Jan Medical, Inc. 2019-12-31
NCT02723344 Biological Signatures, Probiotic Among Those With mTBI and PTSD https://ClinicalTrials.gov/show/NCT02723344 Completed VA Office of Research and Development 2019-05-31
NCT02721537 Use of 31P MRS to Assess Brain NAD+ in Healthy Current and Former Collegiate Athletes https://ClinicalTrials.gov/show/NCT02721537 Recruiting Mayo Clinic 2020-12-31
NCT02701842 ImPACT Online Clinical Study https://ClinicalTrials.gov/show/NCT02701842 Completed ImPACT Applications, Inc. 2016-06-30
NCT02690584 Metacognitive Therapy for Post-concussive Symptoms After Mild Traumatic Brain Injury https://ClinicalTrials.gov/show/NCT02690584 Recruiting Norwegian University of Science and Technology 2020-11-30
NCT02634944 The Use of the VOMS Tool With Military Personnel to Track mTBI Recovery and RTD Status https://ClinicalTrials.gov/show/NCT02634944 Completed University of Pittsburgh 2020-02-29
NCT02597504 Development of a Neurocognitive Screening Test https://ClinicalTrials.gov/show/NCT02597504 Active, not recruiting ImPACT Applications, Inc. 2019-09-30
NCT00857207 Metacognitive Training to Enhance Strategy Use in Blast-Related TBI https://ClinicalTrials.gov/show/NCT00857207 Completed VA Office of Research and Development 2019-12-23
NCT02556177 Advanced MRI Applications for Mild Traumatic Brain Injury-Phase 2 https://ClinicalTrials.gov/show/NCT02556177 Completed GE Healthcare 2018-01-31
NCT03391583 Can Targeted Education Impact the Current Standard of Care in Patients With Mild Traumatic Brain Injury? https://ClinicalTrials.gov/show/NCT03391583 Recruiting St. Michael’s Hospital, Toronto 2019-12-17
NCT02455037 Evaluation of a Neck Strengthening Program to Reduce the Risk of Sport-related Concussion https://ClinicalTrials.gov/show/NCT02455037 Completed University of Michigan 2015-10-31
NCT02453958 Mild Traumatic Brain Injury Discrimination https://ClinicalTrials.gov/show/NCT02453958 Completed Empirical Technologies Corporation 2012-12-31
NCT02383472 LED Therapy for the Treatment of Concussive Brain Injury https://ClinicalTrials.gov/show/NCT02383472 Completed Boston Children’s Hospital 2016-05-31
NCT02374918 Bright Light Therapy for Treatment of Sleep Problems Following Mild Traumatic Brain Injury https://ClinicalTrials.gov/show/NCT02374918 Completed University of Arizona 2019-09-30
NCT02368366 Comparative Effectiveness of Family Problem-Solving Therapy (F-PST) for Adolescent TBI https://ClinicalTrials.gov/show/NCT02368366 Completed Children’s Hospital Medical Center, Cincinnati 2017-11-30
NCT02362347 Investigating Novel Treatments for Concussion: Impact of Compression Vest on Rehabilitation Outcomes https://ClinicalTrials.gov/show/NCT02362347 Completed Western University, Canada 2019-03-04
NCT02337101 Early Intervention Programme for Young Patients (Aged 15 - 30 Years) With Symptoms Following Concussion. https://ClinicalTrials.gov/show/NCT02337101 Completed University of Aarhus 2018-07-31
NCT02299128 Effectiveness of Early Physical Therapy Intervention for Patients With Dizziness After a Sports-Related Concussion https://ClinicalTrials.gov/show/NCT02299128 Completed Walsh University 2015-12-31
NCT02280304 Meditation in Veterans With PTSD and Mild TBI https://ClinicalTrials.gov/show/NCT02280304 Completed VA Office of Research and Development 2017-06-30
NCT02276079 The Effect of Exercise on Neurorecovery Following Mild Traumatic Brain Injury https://ClinicalTrials.gov/show/NCT02276079 Completed University of Florida 2016-12-22
NCT02266329 Chronic Postconcussive Headache: A Placebo-Controlled Treatment Trial of Prazosin https://ClinicalTrials.gov/show/NCT02266329 Recruiting VA Office of Research and Development 2021-09-30
NCT02260570 Remediation of Impaired Self-Regulation in Patients With Mild TBI https://ClinicalTrials.gov/show/NCT02260570 Active, not recruiting VA Office of Research and Development 2020-06-29
NCT02114775 Growth Hormone or Sildenafil as Therapies for Fatigue in Mild- Traumatic-brain-injury (MTBI) https://ClinicalTrials.gov/show/NCT02114775 Completed The University of Texas Medical Branch, Galveston 2017-11-10
NCT02084329 Balance and Mild Traumatic Brain Injury: The Effect of a Weighted Compression Vest https://ClinicalTrials.gov/show/NCT02084329 Recruiting Lawson Health Research Institute 2021-04-30
NCT02069795 Speech Analysis as a Diagnostic Tool for Mild Traumatic Brain Injury https://ClinicalTrials.gov/show/NCT02069795 Completed Methodist Sports Medicine 2014-08-31
NCT01306968 Hyperbaric Oxygen Therapy (HBO2) for Persistent Post-concussive Symptoms After Mild Traumatic Brain Injury (mTBI) https://ClinicalTrials.gov/show/NCT01306968 Completed U.S. Army Medical Research and Development Command 2012-08-31
NCT02057081 Multifamily Group to Reduce Marital Conflict and Disability in Veterans With mTBI https://ClinicalTrials.gov/show/NCT02057081 Completed VA Office of Research and Development 2019-03-12
NCT04280965 Quetiapine Augmentation of PE Therapy for the Treatment of Co-occurring PTSD and Mild Traumatic Brain Injury https://ClinicalTrials.gov/show/NCT04280965 Recruiting The University of Texas Health Science Center at San Antonio 2020-12-31
NCT01975857 Mind-Body Rehabilitative Program for Veterans With mTBI (Mild Traumatic Brain Injury) https://ClinicalTrials.gov/show/NCT01975857 Completed University of Utah 2018-02-28
NCT01947504 Early Intervention Following Mild TBI https://ClinicalTrials.gov/show/NCT01947504 Completed McGill University Health Centre/Research Institute of the McGill University Health Centre 2018-08-31
NCT01921179 Rehabilitation of Executive Functioning in Veterans With PTSD and Mild TBI https://ClinicalTrials.gov/show/NCT01921179 Completed VA Office of Research and Development 2018-12-30
NCT01903525 DHA For The Treatment of Pediatric Concussion Related to Sports Injury https://ClinicalTrials.gov/show/NCT01903525 Active, not recruiting University of Texas Southwestern Medical Center 2020-06-30
NCT01860404 BCAA’s in Concussion https://ClinicalTrials.gov/show/NCT01860404 Active, not recruiting Children’s Hospital of Philadelphia 2022-01-31
NCT01815125 Ondansetron for Pediatric Mild Traumatic Brain Injury https://ClinicalTrials.gov/show/NCT01815125 Completed St. Justine’s Hospital 2014-02-28
NCT01814527 High Dose Omega-3 Fatty Acids in the Treatment of Sport Related Concussions https://ClinicalTrials.gov/show/NCT01814527 Completed East Carolina University 2017-07-31
NCT01747811 Effects of Bright Light Therapy in Mild Traumatic Brain Injury https://ClinicalTrials.gov/show/NCT01747811 Completed University of Arizona 2013-12-31
NCT01728142 Comparison of the DANA to the ANAM in the Evaluation of Cognitive Changes After Concussion https://ClinicalTrials.gov/show/NCT01728142 Completed Henry M. Jackson Foundation for the Advancement of Military Medicine 2014-08-31
NCT01728129 DANA Compared to MACE in Evaluation of Suspected Acute Concussion https://ClinicalTrials.gov/show/NCT01728129 Completed Henry M. Jackson Foundation for the Advancement of Military Medicine 2014-11-30
NCT01695577 Vestibular Rehabilitation and Balance Training After Traumatic Brain Injury https://ClinicalTrials.gov/show/NCT01695577 Completed Oslo University Hospital 2016-08-30
NCT01640158 Broad-spectrum Cognitive Remediation: Effects of a Brain Plasticity-based Program in Mild Traumatic Brain Injury https://ClinicalTrials.gov/show/NCT01640158 Completed Posit Science Corporation 2017-03-02
NCT01614444 Acupressure and Stress Resilience https://ClinicalTrials.gov/show/NCT01614444 Completed VA Eastern Colorado Health Care System 2014-08-11
NCT01398566 Clinical Trial of a Rehabilitation Game - SuperBetter https://ClinicalTrials.gov/show/NCT01398566 Completed Ohio State University 2015-01-31
NCT01339806 The Study of Cognitive Rehabilitation Effectiveness for Mild Traumatic Brain Injury https://ClinicalTrials.gov/show/NCT01339806 Completed Brooke Army Medical Center 2014-06-30
NCT04426188 " Acute Brain Changes After Repetitive Headers in Soccer and the Effects of a Protective Device " https://ClinicalTrials.gov/show/NCT04426188 Recruiting University Hospital, Bordeaux 2021-06-30
NCT04248218 Concussion Active Rehabilitation https://ClinicalTrials.gov/show/NCT04248218 Enrolling by invitation Children’s National Research Institute 2020-07-31
NCT04199247 Early Exercise to Improve Psychosocial Function After Pediatric Mild Traumatic Brain Injury https://ClinicalTrials.gov/show/NCT04199247 Recruiting University of Colorado, Denver 2023-01-15
NCT04140084 Wiki Head CT Choice Study: Adaptation of US Two Decision Aids to a Québec Local Context https://ClinicalTrials.gov/show/NCT04140084 Recruiting Laval University 2020-02-15
NCT04122274 Comparing and Interactive Concussion Education Platform to Current Education Standards https://ClinicalTrials.gov/show/NCT04122274 Enrolling by invitation University of North Carolina, Chapel Hill 2020-12-31
NCT04121780 Growth Hormone Replacement Therapy for Retried Professional Football Players https://ClinicalTrials.gov/show/NCT04121780 Recruiting Center for Neurological Studies 2022-03-31
NCT04099329 One Team: Changing the Culture of Youth Sport With Pregame Safety Huddles https://ClinicalTrials.gov/show/NCT04099329 Recruiting Seattle Children’s Hospital 2020-06-01
NCT04079907 Ketone Supplementation in Adolescents Post-Concussion https://ClinicalTrials.gov/show/NCT04079907 Recruiting University of Alabama at Birmingham 2020-10-17
NCT04068883 Controlled DTI Evaluations in High School Football and Female Soccer to Evaluate Efficacy of Jugular Compression Collar https://ClinicalTrials.gov/show/NCT04068883 Active, not recruiting Children’s Hospital Medical Center, Cincinnati 2019-06-30
NCT04043442 rTMS Target Identification for Functional Disability in AUD+mTBI https://ClinicalTrials.gov/show/NCT04043442 Recruiting VA Office of Research and Development 2023-07-01
NCT04036916 Sensorimotor Training for Injury Prevention in Collegiate Soccer Players II https://ClinicalTrials.gov/show/NCT04036916 Completed University of Mississippi Medical Center 2019-12-10
NCT03237468 Neck Strengthening Program for the Prevention or Mitigation of Sports Concussion https://ClinicalTrials.gov/show/NCT03237468 Active, not recruiting CentraCare 2020-06-30
NCT04012853 Remotely Supervised Transcranial Direct Current Stimulation for Persistent Post-traumatic Headache https://ClinicalTrials.gov/show/NCT04012853 Recruiting VA Office of Research and Development 2021-10-30
NCT04001192 Exercise in Patients With Post-Concussion Symptoms https://ClinicalTrials.gov/show/NCT04001192 Recruiting St. Olavs Hospital 2021-04-30
NCT03995173 Pilot rTMS for AUD+mTBI https://ClinicalTrials.gov/show/NCT03995173 Recruiting VA Office of Research and Development 2020-04-30
NCT03989999 Transcranial Ultrasonography for the Management of Patients With Mild TBI https://ClinicalTrials.gov/show/NCT03989999 Recruiting University Hospital, Grenoble 2022-05-31
NCT03974360 Efficacy and Tolerability of Erenumab in the Prophylactic Treatment of Persistent Post-Traumatic Headache https://ClinicalTrials.gov/show/NCT03974360 Completed Danish Headache Center 2019-12-31
NCT03972579 Behavioral Profile Matching: A Precision Medicine Approach to Concussion Rehabilitation https://ClinicalTrials.gov/show/NCT03972579 Active, not recruiting University of British Columbia 2021-02-15
NCT03952208 Neurocognitive Dysfunction After Anesthesia in Patients With Recent Concussion https://ClinicalTrials.gov/show/NCT03952208 Recruiting Mayo Clinic 2021-12-31
NCT03917290 A Sports Injury Prevention Program to Reduce Subsequent Injuries After Concussion https://ClinicalTrials.gov/show/NCT03917290 Recruiting University of Colorado, Denver 2021-04-30
NCT03913975 Effects of Neuromuscular Training on EEG Adaptations in Young Athletes https://ClinicalTrials.gov/show/NCT03913975 Completed Children’s Hospital Medical Center, Cincinnati 2016-12-31
NCT03895450 Treating Persistent Post-concussion Symptoms With Exercise https://ClinicalTrials.gov/show/NCT03895450 Active, not recruiting University of Calgary 2021-09-30
NCT03889483 Neurophysiological Measurements Using the NeuroCatchâ„¢ Platform in Pediatric Concussion https://ClinicalTrials.gov/show/NCT03889483 Recruiting Alberta Children’s Hospital 2020-11-30
NCT03883451 Evaluation of Helmet Technology and Head Impact Exposure https://ClinicalTrials.gov/show/NCT03883451 Active, not recruiting Children’s Hospital Medical Center, Cincinnati 2020-12-10
NCT03865433 The Effect of a Sub-symptom Threshold Aerobic Exercise Program on Recovery in Concussed Athletes https://ClinicalTrials.gov/show/NCT03865433 Recruiting Rocky Mountain University of Health Professions 2020-07-01
NCT03811626 Efficacy of Multidimensional Management of Mild Traumatic Brain Injury https://ClinicalTrials.gov/show/NCT03811626 Completed Institut de Recherche sur la Moelle épinière et l’Encéphale 2013-06-30
NCT03799458 High-Definition Transcranial Direct Current Stimulation (HD-tDCS) for Sensory Deficits in Complex Traumatic Brain Injury https://ClinicalTrials.gov/show/NCT03799458 Recruiting University of New Mexico 2021-09-30
NCT03786276 Virtual Reality- Working Memory Retraining https://ClinicalTrials.gov/show/NCT03786276 Completed University of California, San Francisco 2020-03-31
NCT03781076 Sleep After Adolescent Concussion https://ClinicalTrials.gov/show/NCT03781076 Recruiting Children’s Hospital Medical Center, Cincinnati 2019-10-31
NCT03759808 Treatment for Patients With Chronic Post-Concussion Symptoms https://ClinicalTrials.gov/show/NCT03759808 Recruiting University of California, Los Angeles 2021-02-01
NCT03759223 Enhanced Problem-Solving Training https://ClinicalTrials.gov/show/NCT03759223 Recruiting VA Office of Research and Development 2023-04-03
NCT03691363 Mobile Subthreshold Exercise Program for Concussion https://ClinicalTrials.gov/show/NCT03691363 Completed Seattle Children’s Hospital 2019-09-01
NCT03691272 rTMS Treatment of Persistent Headache and Post Concussion Symptoms Attributed to Mild Traumatic Injury to the Head https://ClinicalTrials.gov/show/NCT03691272 Completed University of Calgary 2018-09-30
NCT03688984 Treatment of Insomnia for Adolescents With Mild Traumatic Brain Injury https://ClinicalTrials.gov/show/NCT03688984 Completed University of Calgary 2018-01-17
NCT03677661 Cervico-vestibular Rehabilitation for Mild Traumatic Brain Injury https://ClinicalTrials.gov/show/NCT03677661 Recruiting Laval University 2020-04-01
NCT03674398 Aerobic Exercise and Cognitive Training Effects on Postconcussive Symptomology https://ClinicalTrials.gov/show/NCT03674398 Completed University of Illinois at Urbana-Champaign 2019-05-03
NCT03653195 Diagnosis of Sport-related Concussion Using Urine Metabolites https://ClinicalTrials.gov/show/NCT03653195 Enrolling by invitation University of Calgary 2019-05-01
NCT03608722 Video Games to Track Cognitive Health https://ClinicalTrials.gov/show/NCT03608722 Active, not recruiting BrainCheck, Inc. 2017-08-31
NCT03600324 Randomized Controlled Trial for Vestibular Treatment in Concussion https://ClinicalTrials.gov/show/NCT03600324 Active, not recruiting University of Pittsburgh 2022-12-31
NCT03598140 Sildenafil Treatment for Mild TBI https://ClinicalTrials.gov/show/NCT03598140 Recruiting University of Texas Southwestern Medical Center 2021-06-30
NCT03582579 Enhancing Brain Training With Virtual Reality https://ClinicalTrials.gov/show/NCT03582579 Recruiting University of Rochester 2021-03-31
NCT03564210 The Effect of Screen Time on Recovery From Concussion https://ClinicalTrials.gov/show/NCT03564210 Recruiting University of Massachusetts, Worcester 2020-07-01
NCT03539848 Diagnosis of mTBI in a Community Setting https://ClinicalTrials.gov/show/NCT03539848 Recruiting University of Miami 2021-06-30
NCT03529799 Disparity Driven Vergence in Mild Traumatic Brain Injury (mTBI) https://ClinicalTrials.gov/show/NCT03529799 Recruiting University of Miami 2020-12-31
NCT03523507 fMRI-neuronavigated rTMS Treatment for Symptoms of Depression Associated With Concussive TBI in the Military Population https://ClinicalTrials.gov/show/NCT03523507 Recruiting Henry M. Jackson Foundation for the Advancement of Military Medicine 2021-07-01
NCT03511339 Pro-2-Cool Device Clinical Study https://ClinicalTrials.gov/show/NCT03511339 Recruiting TecTraum Inc. 2020-01-31
NCT03479541 Can Early Initiation of Rehabilitation With Wearable Sensor Technology Improve Outcomes in mTBI? https://ClinicalTrials.gov/show/NCT03479541 Recruiting Oregon Health and Science University 2021-09-30
NCT03417492 Cerebrovascular Reactivity in American Football Players https://ClinicalTrials.gov/show/NCT03417492 Recruiting University of Pennsylvania 2021-03-01
NCT03414242 Investigation of Neurocognitive Measures of Sport-Related Injury https://ClinicalTrials.gov/show/NCT03414242 Enrolling by invitation Mayo Clinic 2021-12-30
NCT01220713 Hyperbaric Oxygen Therapy (HBO2T) for Post-Concussive Symptoms (PSC) After Mild Traumatic Brain Injury (mTBI) https://ClinicalTrials.gov/show/NCT01220713 Completed Virginia Commonwealth University 2013-07-31
NCT01101724 Effect of Early Rest on Recovery From Pediatric Concussion https://ClinicalTrials.gov/show/NCT01101724 Completed Medical College of Wisconsin 2011-12-31
NCT00893347 An Intervention Program to Reduce to the Risk of Persistent Symptoms After Concussion https://ClinicalTrials.gov/show/NCT00893347 Completed University of British Columbia 2012-07-31
NCT00869154 Multidisciplinary Treatment in Patients With Mild Traumatic Brain Injury https://ClinicalTrials.gov/show/NCT00869154 Completed Haukeland University Hospital 2013-03-31
NCT03869970 Active Injury Management (AIM) After Pediatric Concussion https://ClinicalTrials.gov/show/NCT03869970 Recruiting Medical College of Wisconsin 2022-03-31
NCT00822263 The Use of Anti-oxidants to Reduce Sequela of Mild Traumatic Brain Injury (mTBI) After Blast Exposure https://ClinicalTrials.gov/show/NCT00822263 Completed Brooke Army Medical Center 2009-03-31
NCT03345550 OPTIMA-TBI Pilot Study https://ClinicalTrials.gov/show/NCT03345550 Recruiting University of Michigan 2020-07-27
NCT03244475 Transcranial Electrical Stimulation for mTBI https://ClinicalTrials.gov/show/NCT03244475 Recruiting VA Office of Research and Development 2021-09-30
NCT03213730 Perceptual-Cognitive Training After a Mild Traumatic Brain Injury: Towards a Sensitive Marker for Recovery https://ClinicalTrials.gov/show/NCT03213730 Active, not recruiting McGill University Health Centre/Research Institute of the McGill University Health Centre 2019-03-01
NCT03791515 Clinical Characteristics and Pathophysiology of Post-Traumatic Headache https://ClinicalTrials.gov/show/NCT03791515 Completed Danish Headache Center 2019-12-01
NCT00483444 Telephone Follow-Up on Outcome After Mild Traumatic Brain Injury https://ClinicalTrials.gov/show/NCT00483444 Completed University of Washington 2006-02-28
NCT00409058 Teen Online Problem Solving (TOPS) - An Online Intervention Following TBI https://ClinicalTrials.gov/show/NCT00409058 Completed Children’s Hospital Medical Center, Cincinnati 2009-11-30
NCT00295074 The Effect of Mild Traumatic Brain Injury on Recovery From Injury https://ClinicalTrials.gov/show/NCT00295074 Completed University of Pittsburgh NA
NCT00142090 Use of Salt-Water Solution to Improve Symptoms in Concussion https://ClinicalTrials.gov/show/NCT00142090 Completed Rady Children’s Hospital, San Diego 2005-12-31
NCT00004730 Magnesium Sulfate For Brain Injury https://ClinicalTrials.gov/show/NCT00004730 Completed University of Washington 2005-05-31

Observational Studiess

#If less then 500 studies

nct_id brief_title link overall_status source primary_completion_date
NCT03381638 Understanding Concussion/Mild Traumatic Brain Injury https://ClinicalTrials.gov/show/NCT03381638 Completed Blinktbi, Inc. 2018-04-17
NCT03319966 Eyetracking and Neurovision Rehabilitation of Oculomotor Dysfunction in Mild Traumatic Brain Injury https://ClinicalTrials.gov/show/NCT03319966 Recruiting Hennepin Healthcare Research Institute 2019-06-30
NCT03313505 PROtein S100B for Mild Trauma of the HEad in Emergency Patients https://ClinicalTrials.gov/show/NCT03313505 Recruiting Centre Hospitalier Princesse Grace 2020-05-31
NCT03265912 Evaluating a Novel Method of EEG Evoked Response Potential Analysis in Concussion Assessment https://ClinicalTrials.gov/show/NCT03265912 Completed ElMindA Ltd 2018-01-16
NCT03214432 Return to Work After Mild Traumatic Brain Injury https://ClinicalTrials.gov/show/NCT03214432 Completed University of Copenhagen 2018-07-04
NCT03104244 Longitudinal Brain Health in Youth Tackle Football Players https://ClinicalTrials.gov/show/NCT03104244 Recruiting More Foundation 2020-08-31
NCT03011983 Neural Injury in Adolescents With Concussion https://ClinicalTrials.gov/show/NCT03011983 Completed Children’s Hospital of Philadelphia 2018-06-01
NCT02992795 Unblinded Data Collection Study of Concussion Using BrainPulse https://ClinicalTrials.gov/show/NCT02992795 Completed Jan Medical, Inc. 2017-05-31
NCT02992327 Biomarker Levels as A Predictor of Concussion Severity OUTcomes (BlacOut) https://ClinicalTrials.gov/show/NCT02992327 Completed HealthPartners Institute 2018-08-06
NCT02957461 Validation of Brain Function Assessment Algorithm for mTBI/Concussion in College Athletes https://ClinicalTrials.gov/show/NCT02957461 Completed BrainScope Company, Inc. 2018-01-31
NCT02916108 Interhemispheric Anterior Delta Desynchronization in Children Who Present to the Emergency Department With Acute Concussion: A Proof of Concept Study https://ClinicalTrials.gov/show/NCT02916108 Recruiting Rambam Health Care Campus 2020-12-31
NCT02868684 Imaging Biomarkers of Mild Traumatic Brain Injury: a Longitudinal Cohort Study https://ClinicalTrials.gov/show/NCT02868684 Recruiting First Affiliated Hospital Xi’an Jiaotong University 2020-08-31
NCT02858544 Concussion in Motor Vehicle Accidents: The Concussion Identification Index https://ClinicalTrials.gov/show/NCT02858544 Completed Clionsky Neuro Systems Inc. 2016-06-30
NCT02776462 Use of Eye Movement Tracking to Detect Oculomotor Abnormality in Traumatic Brain Injury Patients https://ClinicalTrials.gov/show/NCT02776462 Completed Oculogica, Inc. 2017-11-16
NCT02771106 Neuroimaging and Neurovision Rehabilitation of Oculomotor Dysfunction in Mild Traumatic Brain Injury https://ClinicalTrials.gov/show/NCT02771106 Active, not recruiting Hennepin Healthcare Research Institute 2020-04-30
NCT02754206 Cerebral Blood Flow Regulation and Concussions https://ClinicalTrials.gov/show/NCT02754206 Recruiting Southern Methodist University 2020-08-31
NCT02661633 Objective Brain Function Assessment of mTBI/Concussion in High School Athletes https://ClinicalTrials.gov/show/NCT02661633 Completed BrainScope Company, Inc. 2017-01-31
NCT02486003 Testing mTBI in Athletes https://ClinicalTrials.gov/show/NCT02486003 Completed University of Miami 2017-08-14
NCT02477943 Objective Brain Function Assessment of mTBI/Concussion in College Athletes https://ClinicalTrials.gov/show/NCT02477943 Completed BrainScope Company, Inc. 2017-02-20
NCT02354469 The Effects of Head Trauma on Collegiate Athletes https://ClinicalTrials.gov/show/NCT02354469 Recruiting Boston Children’s Hospital 2023-08-31
NCT02350894 Microstructural Changes in the Brain During Recovery After Mild Traumatic Brain Injury https://ClinicalTrials.gov/show/NCT02350894 Completed University of Aarhus 2018-02-28
NCT02331901 Cerebral Microstructural Changes Following Mild Traumatic Brain Injury https://ClinicalTrials.gov/show/NCT02331901 Completed University of Aarhus 2016-09-30
NCT02317107 Examination of Balance, Vestibular, and Ocular Functions and Activity Following Concussion https://ClinicalTrials.gov/show/NCT02317107 Active, not recruiting Boston Children’s Hospital 2020-01-01
NCT02171312 Clinical Evaluation of a Novel Balance, Vestibular and Oculomotor Assessment Tool https://ClinicalTrials.gov/show/NCT02171312 Completed Emory University 2015-09-30
NCT02069613 Multimodal Approach to Testing the Acute Effects of Mild Traumatic Brain Injury (mTBI) https://ClinicalTrials.gov/show/NCT02069613 Completed Huntington Medical Research Institutes 2017-08-01
NCT01925963 Normative Datasets for Assessments Planned for Mild Traumatic Brain Injury (NORMAL) https://ClinicalTrials.gov/show/NCT01925963 Completed Intermountain Health Care, Inc. 2016-01-06
NCT01922531 Defining Axonal Injury in Children With Mild Traumatic Brain Injury https://ClinicalTrials.gov/show/NCT01922531 Completed Children’s Hospital Medical Center, Cincinnati 2012-08-31
NCT01847040 Deployment Related Mild Traumatic Brain Injury (mTBI) https://ClinicalTrials.gov/show/NCT01847040 Completed The Defense and Veterans Brain Injury Center 2013-08-31
NCT01832714 Assessment of Oculomotor, Vestibular and Reaction Time Response Following a Concussive Event https://ClinicalTrials.gov/show/NCT01832714 Completed Neuro Kinetics 2015-08-31
NCT01688869 Mild Traumatic Brain Injury Registry https://ClinicalTrials.gov/show/NCT01688869 Completed Atrium Health 2015-01-31
NCT01673464 A Prospective Study of Brain Network Activation (BNA) Changes in High School Athletes Following Concussion https://ClinicalTrials.gov/show/NCT01673464 Completed ElMindA Ltd 2014-04-30
NCT01661075 Quantification of Balance in Acutely Concussed Athletes https://ClinicalTrials.gov/show/NCT01661075 Completed Oregon Health and Science University 2016-06-30
NCT01625962 Brain Indices of Risk for Posttraumatic Stress Disorder (PTSD) After Mild Traumatic Brain Injury (mTBI) https://ClinicalTrials.gov/show/NCT01625962 Completed INTRuST, Post-Traumatic Stress Disorder - Traumatic Brain Injury Clinical Consortium 2015-03-31
NCT01535339 Evaluating a Novel Method of EEG Evoked Response Potential Analysis in Sport Concussion Assessment - Test Stability and Effect of Concussion https://ClinicalTrials.gov/show/NCT01535339 Completed ElMindA Ltd 2015-12-31
NCT01377454 Balance and Mild Traumatic Brain Injury (TBI) https://ClinicalTrials.gov/show/NCT01377454 Completed Oregon Health and Science University 2012-08-31
NCT01334528 Consistency of Automated Neuropsychological Assessment Metrics (ANAM) Performance in Those With Deployment Acquired Mild Traumatic Brain Injury (TBI) https://ClinicalTrials.gov/show/NCT01334528 Completed VA Eastern Colorado Health Care System 2016-01-31
NCT04381767 EYE-SYNC Concussion Classification Study https://ClinicalTrials.gov/show/NCT04381767 Completed Sync-Think, Inc. 2020-03-23
NCT04109677 AIM CONTROL and SWECON - Handball The SWEdish CONcussion Study in Elite Handball https://ClinicalTrials.gov/show/NCT04109677 Enrolling by invitation Linkoeping University 2020-09-30
NCT04107844 Safe Return to Play After Concussion https://ClinicalTrials.gov/show/NCT04107844 Recruiting University College of Northern Denmark 2023-12-31
NCT04095377 Development of Automated Analysis to Electroencephelogram (EEG) Data in Patients Treated at the Sagol Hyperbaric Medicine and Research Center at the Years 2017-2019. https://ClinicalTrials.gov/show/NCT04095377 Active, not recruiting QuantalX Neuroscience 2020-03-31
NCT04074486 Evaluation and Validation of a Multimodal Brain Function Biomarker With NPC https://ClinicalTrials.gov/show/NCT04074486 Recruiting BrainScope Company, Inc. 2021-03-30
NCT04032509 A Study of Biomarkers of Mild Traumatic BRAIN Injury https://ClinicalTrials.gov/show/NCT04032509 Recruiting University Hospital, Grenoble 2020-11-30
NCT03963804 Objective Brain Function Assessment of mTBI/Concussion https://ClinicalTrials.gov/show/NCT03963804 Completed BrainScope Company, Inc. 2019-01-25
NCT03892356 Oculomotor Function Testing in Acute Concussion https://ClinicalTrials.gov/show/NCT03892356 Recruiting University Health Network, Toronto 2021-04-30
NCT03892291 Objective Dual-task Turning Measures for Return-to-duty Assessments https://ClinicalTrials.gov/show/NCT03892291 Recruiting Oregon Health and Science University 2022-09-30
NCT03777228 Integrated Eye Tracking and Neural Monitoring for Enhanced Assessment of Mild TBI: Primary Study https://ClinicalTrials.gov/show/NCT03777228 Completed Uniformed Services University of the Health Sciences 2017-03-15
NCT03678077 Trends in Cohabitation Status, Academic Achievement and Socio-economic Indicators After Mild Traumatic Brain Injury https://ClinicalTrials.gov/show/NCT03678077 Completed University of Copenhagen 2019-03-13
NCT03624634 Assessment of the Effects of Concussion on Adolescent Rugby Union Players https://ClinicalTrials.gov/show/NCT03624634 Recruiting Sports Surgery Clinic, Santry, Dublin 2018-12-31
NCT03544372 Reliability of Self-reported Concussion History in Current Rugby Union Players https://ClinicalTrials.gov/show/NCT03544372 Completed University of Dublin, Trinity College 2017-12-20
NCT01044615 Advanced Imaging Tools in the Study of Mild Traumatic Brain Injury https://ClinicalTrials.gov/show/NCT01044615 Completed Kettering Health Network NA
NCT01021137 Vestibular Consequences of Blast-related Mild Traumatic Brain Injury (TBI) https://ClinicalTrials.gov/show/NCT01021137 Completed VA Office of Research and Development 2016-12-30
NCT00822445 S100 Protein in Minor/Mild Traumatic Brain Injury https://ClinicalTrials.gov/show/NCT00822445 Completed Assistance Publique - Hôpitaux de Paris 2010-05-31
NCT03671083 Validation of Brain Function Assessment Algorithm for mTBI/Concussion https://ClinicalTrials.gov/show/NCT03671083 Completed BrainScope Company, Inc. 2019-03-01
NCT02901821 Predicting Concussion Outcomes With Salivary miRNA https://ClinicalTrials.gov/show/NCT02901821 Recruiting Milton S. Hershey Medical Center 2021-12-31
NCT00724607 Brain Injury Outcomes (BIO) Study https://ClinicalTrials.gov/show/NCT00724607 Recruiting VA Office of Research and Development 2020-06-30
NCT00717301 S-100B as Pre-Head CT Scan Screening Test After Mild Traumatic Brain Injury https://ClinicalTrials.gov/show/NCT00717301 Completed University of Rochester 2010-09-30
NCT00715949 Neurocognitive Evaluation of Mild Traumatic Brain Injury in the Hospitalized Pediatric Population https://ClinicalTrials.gov/show/NCT00715949 Completed Children’s Hospital of Philadelphia 2007-12-31

Registries

#If less then 500 registries

nct_id brief_title link overall_status source primary_completion_date
NCT02977728 Olfactory Function in Patients With Acute Mild Traumatic Brain Injury https://ClinicalTrials.gov/show/NCT02977728 Completed Hôpital de Viege 2018-04-30
NCT02161172 Cognitive and Psychosocial Outcome After Mild Traumatic Brain Injury https://ClinicalTrials.gov/show/NCT02161172 Completed Shanghai 6th People’s Hospital 2014-04-30
NCT03966404 EyeBOX Concussion Study and Registry https://ClinicalTrials.gov/show/NCT03966404 Recruiting Oculogica, Inc. 2021-06-30